PMSG is a potent gonadotrophin, with dual FSH and LH activity. It is
composed of two non-covalently associated alpha and beta subunits, and
is heavily glycosylated on its CTP tail. This extensive glycosylation is
of key importance for obtaining the extended half life in blood typical
of PMSG. As PMSG binds to FSH and LH receptors, it stimulates
follicular growth and follicular maturation during the days preceding
oestrus and ovulation. Limited amounts of PMSG will result in induction
and synchronization of ovulation in cattle and small ruminants,
irrespective of their cyclicity prior to treatment. Administration of
slightly higher amounts will modestly increase ovulation rate and litter
size. Administration of high amounts of PMSG will result in
superovulation, therefore resulting in the numerous blastocysts needed
for embryo transfer. PMSG also has the potential to induce puberty in
swine.
Generic Name: Serum Gonadotrophin for Injection…